Chris Neil made it 4-1 at the 8:12 mark of the second period, but the Sabres responded less than a minute later on Jordan Leopold's first. The Buffalo defenseman redirected a Jochen Hecht pass past Anderson to cut the deficit in half. The Sabres pulled to within a goal when Jason Pominville was credited with his sixth of the season. The goal was allowed to stand following a review to see if the Buffalo captain used his skate to kick the puck into the net. Buffalo came close to tying it up in the game's final minutes, but couldn't finish off a wild scrum in front of the Ottawa net.
Enroth finished with 20 saves on 24 shots, falling to 0-10-3 in his last 13 starts.
The Sabres return home to face the Montreal Canadiens on Thursday at First Niagara Center. Pregame gets underway on WGR at 6 p.m., followed by the 7 p.m. faceoff with Rick Jeanneret and Rob Ray on the Sabres Radio Network.
8:15 - OTT - Erik Karlsson (PPG) (4) (Kyle Turris)
8:36 - BUF - Tyler Ennis (3) (Drew Stafford, Jordan Leopold)
14:15 - OTT - Daniel Alfredsson (2) (Mika Zibanejad)
7:48 - BUF - Adam Pardy (2 min., holding)
11:21 - OTT - Zack Smith (2 min., closing hand on puck)
9:09 - BUF - Jordan Leopold (1) (Jochen Hecht, Steve Ott)
3:07 - OTT - Bench penalty (2 min., too many men on the ice)
14:14 - OTT - Erik Condra (2 min., hooking)
18:13 - OTT - Marc Methot (2 min., holding)
13:55 - BUF - Jason Pominville (6) (Cody Hodgson, Adam Pardy)
19:45 - BUF - Cody Hodgson (2 min., tripping)
BUF - Jhonas Enroth (20 saves, 24 shots)
OTT - Craig Anderson (20 saves, 23 shots)
BUF - 0 of 4
OTT - 1 of 2
1.) Daniel Alfredsson (1 G, 0 A)
2.) Erik Karlsson (1 G, 0 A)
3.) Kyle Turris (0 G, 1 A)